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Los mecanismos combinados abordan el metabolismo de las grasas tanto en la fase de eliminacin activa (eliminacin facilitada por cidos biliares) como en la fase de acumulacin pasiva (supresin de la adipognesis), lo que significa que la grasa liberada se elimina ms rpido Y la formacin de nueva grasa se ralentiza simultneamente

the definition of this profile showed a good level of homogeneity (mean inter-item Spearman 0.25) [41] and has been extensively described previously as belonging to the immuno-metabolic depression (IMD) domain, based on previous findings on individual symptoms with immuno-metabolic dysregulation [2]

The next morning, the cells were washed using 2% FACS buffer and incubated in secondary antibody (Table S12) for 1 h on ice

HFD mice showed mitochondrial swelling, and cristae disorganization